Top 10 Largest US Startup Funding Rounds This Week: Major Investments in Medical Devices, AI Innovations, and Frontier Labs

Explore the biggest startup funding events in the US for the week of May 18-22, 2026, highlighting over $100 million deals that shape the tech landscape. Leading the pack is MiRus, which secured a $1.5 billion corporate investment led by Boston Scientific for advanced orthopedic and spinal solutions. Hot on their heels, Hark raised $700 million in a Series A to pioneer personalized AI hardware, supported by industry giants like Nvidia and Intel Capital. Other significant funding rounds include Modal Labs' $355 million for AI infrastructure, Decart's and Amca’s $300 million deals in generative AI and aerospace defense, respectively, and Mercury’s $200 million Series D fueling fintech growth. These investments underline a strong trend in physical technology, frontier labs, and AI-driven innovations, reflecting robust investor confidence across sectors such as healthcare, AI, fintech, and aerospace. Stay tuned for the latest developments in startup innovation and funding.